*Disclaimer: Just because you can’t take CBD orally, doesn’t mean you can’t fuel the endocannabinoid system! While some may not be able to use capsules, tinctures, or edibles – there are other options such as healing bath salts, topicals (salves/lotions), suppositories, patches, and pre-rolls!


Photo by Peter Gombos on Unsplash

Mixing CBD and pharmaceuticals?

First of all, fueling the endocannabinoid system will likely be of great benefit to those most in need of pharmaceutical meditation. Yet, while most pharmaceuticals are fine to take alongside cannabinoids, there are some potential issues that are very important to be aware of.

If one is on a medication that is digested by the CPY3A4 family of liver enzymes, taking CBD orally may not be a good option for you. CBD temporarily inhibits Cytochrome P450, which metabolizes up to 65% of the pharmaceutical meditations people consume. Therefore, when this digestive process takes place, the body will most likely break down the CBD rather than the
pharmaceutical, which can cause the pharmaceuticals to build up in the body, and an overabundance of pharmaceuticals in the body can lead to exaggerated, unwanted, and potentially harmful effects.

How can I tell if this is my medication?

Of course, it is best to talk to your doctor. CBD is a deeply therapeutic, truly changing body at a cellular level, and should be discussed with a medical professional as any medication would be. Studies are underway to determine which medication CBD should and should not be mixed with—but we have a fairly standard rule—if you can’t take grapefruit while on the medication?
You probably shouldn’t take CBD orally. In grapefruit, there is a chemical, furanocoumarins, which inhibits the CYP3A4, similar to CBD.

There are other options to help fuel the endocannabinoid system!!


Photo by Maddi Bazzocco on Unsplash

Those who have skin difficulties/joint issues:

Topicals. (Anything you put on your skin, including patches and bath salts.)

Studies have shown when CBD is applied topically, it results in a meaningful accumulation of cannabinoids in the skin and the underlying muscle. Additionally, this delivery mechanism is extremely bioavailable, provides the ability to target specific areas of the body, and serves as support for issues ranging from inflammation and circulation to dryness.

Those who have muscle aches/nerve problems/stomach issues:

Bath Salts.

My all time favorite products! When the skin heats up and soaks in all of the cannabinoids, it’s
nothing short of divine.


With a 90% bioavailability rate, the highest there is, there’s no wonder these are the most
in-demand and re-ordered products around. They stay on the body for up to 92 hours with a slow
but steady release of cannabinoids.


Hemp joints are the most potent delivery mechanism! These will help soothe the pain instantly!

CBD Suppositories.

Not only do these go directly into the bloodstream, but they are also extremely supportive for
those suffering from lower body pain.

Those with stress/neurodegeneration/other brain issues:

CBD Pre-Rolls.

The cannabinoids will go straight to the brain—where they are needed! You will not be high at
all, only very, very mellow. More mellow than you’ve ever been.

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