- An endocannabinoid.
- The “bliss” molecule.
- Activates the CB receptors / fuels the endocannabinoid system.
- CBD inhibits the FAAH enzyme, which breaks down anandamide.
- Led the prohibition of the cannabis sativa plant in the 1930s.
- Inhibits oxidation.
- Too much oxidation = free radicals.
- Free radicals = damage to the cells of the body.
- Accumulates the substances, such as pesticides or toxins, in the soil and cleans the soil of them.
- Percentage of drug absorption with consumption.
- Full spectrum (a whole plant product) with the THC removed.
- Chemical compounds that act on cannabinoid receptors in the body.
- There are endocannabinoids (made by the body), phytocannabinoids (made by plants), and synthetic cannabinoids (made in a lab).
- Of the cannabis sativa plant family.
- The plant with high levels of THC (psychoactive properties).
- Cousin to the hemp plant.
CB 1 Receptor
- the primary receptors of the nervous system.
- There are high levels of CB1 receptors in the brain, but they can also be found throughout the body, in the adrenal glands, adipose tissue, heart, liver, lung, prostate, uterus, ovary testis, bone marrow, thymus, and tonsils.
CB 2 Receptor
- the peripheral cannabinoid receptors.
- not expressed in neurons as CB1 is.
- primary expressions are in the immune system, but are also found in bones, the GI system, and microglia of the central nervous system.
Central Nervous System
- Through the brain and spinal cord, this system brings together information coming from every part of the body and coordinates actions.
Certificate of Analysis
- Results of lab tests performed to determine both the chemical makeup and possible toxins inside of the specific batch of product.
- The level of health that the molecules which make up the cell (proteins, mitochondria, and DNA) are functioning at.
- A persistent disease/condition.
- A high level of stress experienced over a substantial amount of time where the person feels little to no control.
- 2+ chronic disease/conditions occurring at the same time.
- The cannabinoids endogenously made by the body.
- The body lacks enough cannabinoids to turn on the CB receptors and, therefore, the endocannabinoid system cannot function properly.
- The system, fueled by cannabinoids, that brings the body to homeostasis.
- FAAH & MAGL = the 2 key enzymes of the endocannabinoid system.
- Molecules that accelerate chemical reaction inside of the body.
- The process of separating a desired cannabinoid from the others.
Depleted Endocannabinoid System
- An endocannabinoid system which lacks the amount of cannabinoids sufficient to fuel the system.
- Invented cellophane, which was set to become the standard packaging for nearly all American products. He feared that hemp fiber would compete against cellophane based products such as synthetic nylon and rayon.
- The enzyme of the endocannabinoid system that breaks down anandamide.
- Gives the plant it’s pigment/color, blocks UV rays, deters predators, and attracts pollinators. For humans, they are great antioxidants with antiinflammatory and antibacterial properties.
- Unstable atoms inside of the body that can damage cells which can, then, lead to both illness and aging.
- Excess free radicals trigger more inflammatory pathways.
Hearst, William Randolph
- He was the head of the newspaper business, the owner of many paper mills, and he feared hemp as a competing paper source. He printed much propaganda against hemp in his newspapers.
- A strain of the cannabis sativa plant.
- Cousin to the cannabis (marijuana) plant.
- Contains high concentrations of CBD and low concentrations of THC.
- The fiber of the cannabis plant can be used to make rope, strong fabrics, fiberboard, and paper.
- An oil without any cannabinoids, terpenes, or flavonoids, but many essential fatty acids (like olive oil).
HPA Axis Pathway The hypothalamic pituitary adrenal (HPA) axis
- This is our stress response system.
- This is the balance in the body which is maintained by physiological processes.
- One cannabinoid is extracted from the rest of the plant.
- One of the 2 key enzymes of the endocannabinoid system.
- Secretary of the Treasury (head of all financial matters in the U.S.), the wealthiest man in the U.S., and a man who was substantially invested in nylon (DuPont’s new synthetic fiber). He thought that the success of nylon was dependent on the eradication of hemp, the traditional fiber, as competition.
- Pain caused by damage to the body.
Pathways (ex. allergic, inflammatory)
- A series of actions taken by the molecules in a cell which lead to physical changes in the cell.
- Outside of the spinal cord and brain.
- The cannabinoids produced by the cannabis sativa plant.
- 113 cannabinoids have been found in the cannabis plant so far.
- CBC (Cannabichromene)
- Binds with receptors in the body besides the CB receptors.
- Potentially beneficial in treating depression, acne, cancer, brain health, pain, and inflammation.
- CBD (Cannabidol)
- Increases the levels of anandamide.
- Promising benefits include (needs further research) antiepileptic, sedative, antipsychotic, and anti-proliferative & pro-apoptotic effects in tumor cell lines.
- CBG (Cannabigerol)
- Potentially useful for the immune system, inflammation, as an antibacterial agent, and shows promise for glaucoma and cancer treatments.
- Is created by the breakdown of THC in older flowers.
- May also have anti-seizure, anti-inflammatory, and antibiotic properties.
- To be confirmed, needs further study.
- THC (Δ9–tetrahydrocannabinol)
- Responsible for the “high” provided by cannabis.
- Activates the CB1 receptors.
- Pain relief / a relaxant.
- May help with PTSD, Insomnia, Inflammation, Nausea, Migraines, Crohn’s disease, Multiple Sclerosis, + more.
- The chemical reaction produced by the body.
- The (hemp) plant cleans the soil by removing all of the toxins.
- The chemical compounds of the plant.
- These initiate the chemical responses that lead to cell growth, division, and death. They convey signals throughout the body.
- Of standard oil, feared hemp as a competing fuel.
- When the whole plant works together to create maximal therapeutic benefits
- Terpenes create the aroma of a plant and provide many health benefits.
- Beta Caryophyllene:
- Anti Inflammatory, Analgesic, Binds to CB2 receptors, Protects cells living in the digestive tract.
- Promising benefits include the anti-bacterial, anti-inflammatory, anti-tumor, and pharmacokinetic properties
- Contains promising abilities to work with Acid reflux, anxiety, and depression.
- Contains promising abilities as an anesthetic, anti-convulsant, analgesic, and an anxiety reliever.
- Contributes to the sedative effects of indica strains of cannabis, a sleep aid, and a muscle relaxant.
- Contains anti-inflammatory, bronchodilator, memory aid, and anti-bacterial
Whole plant extract
- An extract that is not removing specific cannabinoids
- 1 of the 2 key enzymes in the endocannabinoid system
3rd Party Testing
- When the makeup of a company’s product is tested for plant compounds and toxins by a 3rd party lab.